Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan-induced diabetic mice

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Antidiabetic activity and phytochemical screening of extracts of the leaves of Ajuga remota Benth on alloxan-induced diabetic mice

BACKGROUND Ajuga remota Benth is traditionally used in Ethiopia for the management of diabetes mellitus. Since this claim has not been investigated scientifically, the aim of this study was to evaluate the antidiabetic effect and phytochemical screening of the aqueous and 70% ethanol extracts on alloxan-induced diabetic mice. METHODS After acute toxicity test, the Swiss albino mice were induc...

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Evaluation of the diuretic activity of the aqueous and 80% methanol extracts of Ajuga remota Benth (Lamiaceae) leaves in mice

BACKGROUND In the Ethiopian traditional medicine, the leaves of Ajuga remota B. (Local name, Armagusa) is used in the treatment of hypertension. Since this claim has not been investigated scientifically, the aim of the present study was to evaluate the diuretic potential of the aqueous and 80% methanol extracts of the leaves of Ajuga remota in mice after acute oral administration. METHODS Adu...

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Phytochemical screening and antidiabetic effect of extracts of the seeds of Citrullus lanatus in alloxan-induced diabetic albino mice

Article history: Received on: 07/09/2014 Revised on: 23/10/2014 Accepted on: 14/12/2014 Available online: 28/03/2015 Diabetes mellitus is a major and current epidemic disease of the human race implicated with numerous clinical manifestations. A number of protein-rich seeds such as that of Citrullus lanatus (watermelon) are commonly used in traditional medicine with increasing acclaimed efficacy...

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Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats

BACKGROUND Stevia rebaudiana regulates blood sugar, prevents hypertension and tooth decay. Other studies have shown that it has antibacterial as well as antiviral property. METHODS Preliminary phytochemical screening of aqueous, ether and methanolic extracts of S. rebaudiana was done. Acute and sub-acute toxicity were conducted on twenty four Albino rats, divided into one control (Group I) an...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2017

ISSN: 1472-6882

DOI: 10.1186/s12906-017-1757-5